Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise
نویسندگان
چکیده
منابع مشابه
A new formula for normal tissue complication probability (NTCP) as a function of equivalent uniform dose (EUD).
To facilitate the use of biological outcome modeling for treatment planning, an exponential function is introduced as a simpler equivalent to the Lyman formula for calculating normal tissue complication probability (NTCP). The single parameter of the exponential function is chosen to reproduce the Lyman calculation to within approximately 0.3%, and thus enable easy conversion of data contained ...
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Purpose: In the current study, using different radiobiological models, tumor control probability (TCP) and normal tissue complication probability (NTCP) of radiotherapy plans were calculated for three-dimensional conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) of prostate cancer.Methods and Materials: 10 prostate plans were randomly selected among patients ...
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The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific NTCP. We emphasise an asymptotic simplification which relates the NTCP to the solution of a logistic differential equation. This framework allows for a direct ...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2012
ISSN: 0167-8140
DOI: 10.1016/j.radonc.2011.10.022